Though the film didn't fare well both financially and critically, this role made him one of the few actors to headline in films based on both Marvel and DC characters. (Rest in Peace Department), which was released in 2013.
He then had starring roles in two Dreamworks Animation feature films; The Croods and Turbo, both released in 2013. Reynolds went on to star in low-budget films, The Voices (2014), The Captive (2014), and Mississippi Grind (2015); before having a supporting role in the financially successful biographical film, Woman in Gold (2015).
Some of his most prominent roles are Billy Simpson in the YTV Canadian teen soap opera Hillside (1991), Michael Bergen on the ABC sitcom Two Guys and a Girl (1998–2001), and various comic book characters including Marvel Comics superheroes Hannibal King in Blade: Trinity (2004), and Wade Wilson / Deadpool in X-Men Origins: Wolverine (2009), Deadpool (2016), and Deadpool 2 (2018); the latter role earned him a Golden Globe Award nomination.
Reynolds' career began in 1991, when he starred as Billy Simpson in the Canadian-produced teen soap opera Hillside, distributed in the United States by Nickelodeon as Fifteen.
In 1996, he had a supporting role as Jay “Boom” De Boom in ”Syzygy”, the thirteenth episode of season three of the X-Files, and co-starred with Melissa Joan Hart in the TV movie Sabrina the Teenage Witch.
Ryan began dating the "You Oughta Know" singer in 2002, and they became something of a match made in Canada.
They got engaged in 2004 but parted ways three years later, and Alanis used their split as inspiration for her Flavors of Entanglement album in 2008.
The film takes place within the larger X-Men film universe, being made possible by the reset timeline in X-Men: Days of Future Past.